剧集《卢克·凯奇》中，这位天赋异禀的角色在纽约市黑人聚集地哈莱姆区重拾生活的过程中，被迫与他所在城市的核心人物，也就是马赫莎拉哈什巴兹·阿里饰演的Cornell Stokes展开斗争，而这一切都迫使他再度面对他想埋葬的过去。
卢克·凯奇这个角色首次出现在《杰西卡·琼斯》之中，他是杰西卡·琼斯的爱人。在剧集中，卢克受重伤在被杰西卡送到医院时，遇到罗莎里奥·道森饰演的Claire Temple，Claire负责照顾卢克直到他清醒。而在《卢克·凯奇》中，观众将继续看到罗莎里奥·道森的身影，而饰演杰西卡·琼斯的克里斯滕·里特将不会参演。
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